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The amount of output current depends on the combined impedance of the electrodes, skin, and tissues. With repetitive electrical stimulation applied to the same location on the skin, the skin impedance is reduced, which could result in greater current flow as stimulation continues.

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Constipation can also alternate with diarrhea. This pattern is more commonly considered as part of the irritable bowel syndrome (IBS). At the extreme end of the constipation spectrum is fecal impaction, a condition in which stool hardens in the rectum and prevents the passage of any stool.

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